Infectious bursal disease (IBD) or Gumboro disease is a highly contagious disease of young chickens caused by infectious bursal disease virus characterized by immunosuppression and mortality. Young birds at around 2 to 8 weeks of age that have highly active bursa of Fabricius are more susceptible to the disease. Birds over 8 weeks are resistant to challenges and will not show clinical signs unless infected by highly virulent strains. Infection is through oral-fecal route (when the bird ingests contaminated faeces). Acute disease and death is due to the destructive effect of the virus on the host tissues. Kidney failure is a common cause of death in affected bird. If the bird survives, it remains immunocompromised which means it is more susceptible to other diseases. Clinical signs: 1. Disease may appear suddenly and spread typically reaches 100%. 2. Mortality commences on the third day of infection, reaches a peak by day 4, then drops rapidly, and the surviving chickens recover
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